The Prophet (may Allah's peace and blessings be upon him) forbade the use of saffron by men
Authentic hadithعن أنس بن مالك رضي الله عنه قال: نهى النبي صلى الله عليه وسلم أن يَتَزَعْفَرَ الرجلُ.
Anas ibn Mālik (may Allah be pleased with him) reported directly that the Prophet (may Allah's peace and blessings be upon him) forbade the use of saffron by men.
Explanation
The Prophet (may Allah's peace and blessings be upon him) forbade men to dye their bodies or clothes with saffron, because saffron was a perfume of the women, So, men were forbidden to use it; to prevent resemblance between both genders.
Source · Narrated by Bukhari & Muslim
From the Hadith Encyclopedia (hadeethenc.com).